Proteomics: Return to the fold | The Economist

Proteomics: Return to the fold | The Economist: "Return to
Proteomics May 8th 2008 | from PRINT EDITION

FOR sheer adrenaline, the new computer game “foldit”, does not match the likes of “Grand Theft Auto IV”. But for the world's obsessive problem solvers, a three-dimensional Tetris which allows them to help design a new life-saving vaccine seems certain to be a hit.

“foldit” is the latest incarnation of a project, called Rosetta@home, that uses spare computer time, via a screensaver, to work out how proteins fold. Proteins are the building blocks of life inside cells; they are first made as long chains of molecules and work properly only after they have folded into their final shape. But understanding the rules of protein folding remains one of biology's central problems."